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Role of IQGAP3 in metastasis and epithelial–mesenchymal transition in human hepatocellular carcinoma

BACKGROUND: Hepatocellular carcinoma (HCC) is one of the most lethal cancers worldwide owing to its high rates of metastasis and recurrence. The oncogene IQ motif-containing GTPase activating protein 3 (IQGAP3) is ubiquitously overexpressed in several human cancers, including liver, ovary, lung, lar...

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Detalles Bibliográficos
Autores principales: Shi, Yongjie, Qin, Nan, Zhou, Qiang, Chen, Yanqiu, Huang, Sicong, Chen, Bo, Shen, Gang, Jia, Hongyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558666/
https://www.ncbi.nlm.nih.gov/pubmed/28810875
http://dx.doi.org/10.1186/s12967-017-1275-8