Modulating cancer cell survival by targeting intracellular cholesterol transport

BACKGROUND: Demand for cholesterol is high in certain cancers making them potentially sensitive to therapeutic strategies targeting cellular cholesterol homoeostasis. A potential approach involves disruption of intracellular cholesterol transport, which occurs in Niemann–Pick disease as a result of...

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Detalles Bibliográficos
Autores principales: Kuzu, Omer F, Gowda, Raghavendra, Noory, Mohammad A, Robertson, Gavin P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558686/
https://www.ncbi.nlm.nih.gov/pubmed/28697173
http://dx.doi.org/10.1038/bjc.2017.200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558686/
https://www.ncbi.nlm.nih.gov/pubmed/28697173
http://dx.doi.org/10.1038/bjc.2017.200

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