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Modulating cancer cell survival by targeting intracellular cholesterol transport

BACKGROUND: Demand for cholesterol is high in certain cancers making them potentially sensitive to therapeutic strategies targeting cellular cholesterol homoeostasis. A potential approach involves disruption of intracellular cholesterol transport, which occurs in Niemann–Pick disease as a result of...

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Detalles Bibliográficos
Autores principales:	Kuzu, Omer F, Gowda, Raghavendra, Noory, Mohammad A, Robertson, Gavin P
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Translational Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558686/ https://www.ncbi.nlm.nih.gov/pubmed/28697173 http://dx.doi.org/10.1038/bjc.2017.200

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