Biological function in the twilight zone of sequence conservation

Strong DNA conservation among divergent species is an indicator of enduring functionality. With weaker sequence conservation we enter a vast ‘twilight zone’ in which sequence subject to transient or lower constraint cannot be distinguished easily from neutrally evolving, non-functional sequence. Twi...

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Detalles Bibliográficos
Autor principal: Ponting, Chris P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558704/
https://www.ncbi.nlm.nih.gov/pubmed/28814299
http://dx.doi.org/10.1186/s12915-017-0411-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558704/
https://www.ncbi.nlm.nih.gov/pubmed/28814299
http://dx.doi.org/10.1186/s12915-017-0411-5

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