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Biological function in the twilight zone of sequence conservation
Strong DNA conservation among divergent species is an indicator of enduring functionality. With weaker sequence conservation we enter a vast ‘twilight zone’ in which sequence subject to transient or lower constraint cannot be distinguished easily from neutrally evolving, non-functional sequence. Twi...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558704/ https://www.ncbi.nlm.nih.gov/pubmed/28814299 http://dx.doi.org/10.1186/s12915-017-0411-5 |