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Intrathecal Resiniferatoxin Modulates TRPV1 in DRG Neurons and Reduces TNF-Induced Pain-Related Behavior

Transient receptor potential vanilloid-1 (TRPV1) is a nonselective cation channel, predominantly expressed in sensory neurons. TRPV1 is known to play an important role in the pathogenesis of inflammatory and neuropathic pain states. Previous studies suggest interactions between tumor necrosis factor...

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Detalles Bibliográficos
Autores principales: Leo, M., Schulte, M., Schmitt, L.-I., Schäfers, M., Kleinschnitz, C., Hagenacker, T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558708/
https://www.ncbi.nlm.nih.gov/pubmed/28831207
http://dx.doi.org/10.1155/2017/2786427