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Validation of β-lactam minimum inhibitory concentration predictions for pneumococcal isolates with newly encountered penicillin binding protein (PBP) sequences

BACKGROUND: Genomic sequence-based deduction of antibiotic minimum inhibitory concentration (MIC) has great potential to enhance the speed and sensitivity of antimicrobial susceptibility testing. We previously developed a penicillin-binding protein (PBP) typing system and two methods (Random Forest...

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Detalles Bibliográficos
Autores principales: Li, Yuan, Metcalf, Benjamin J., Chochua, Sopio, Li, Zhongya, Gertz, Robert E., Walker, Hollis, Hawkins, Paulina A., Tran, Theresa, McGee, Lesley, Beall, Bernard W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558719/
https://www.ncbi.nlm.nih.gov/pubmed/28810827
http://dx.doi.org/10.1186/s12864-017-4017-7