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Recombinant SFRP5 protein significantly alleviated intrahepatic inflammation of nonalcoholic steatohepatitis

BACKGROUND: Secreted frizzled-related protein 5 (SFRP5) is an anti-inflammatory adipokine modulating metabolism dysfunction. This study aims to observe the effect of recombinant SFRP5 protein on nonalcoholic steatohepatitis (NASH). METHODS: We set up a prokaryotic expression system and purified the...

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Detalles Bibliográficos
Autores principales: Chen, Lili, Zhao, Xiaolong, Liang, Guangjun, Sun, Jiuru, Lin, Zhifeng, Hu, Renming, Chen, Peili, Zhang, Zhaoyun, Zhou, Linuo, Li, Yiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558761/
https://www.ncbi.nlm.nih.gov/pubmed/28824700
http://dx.doi.org/10.1186/s12986-017-0208-0