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Conformational dynamics of the frameshift stimulatory structure in HIV-1

Programmed ribosomal frameshifting (PRF) in HIV-1 is thought to be stimulated by a hairpin in the mRNA, although a pseudoknot-like triplex has also been proposed. Because the conformational dynamics of the stimulatory structure under tension applied by the ribosomal helicase during translation may p...

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Detalles Bibliográficos
Autores principales: Ritchie, Dustin B., Cappellano, Tonia R., Tittle, Collin, Rezajooei, Negar, Rouleau, Logan, Sikkema, William K.A., Woodside, Michael T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558907/
https://www.ncbi.nlm.nih.gov/pubmed/28522581
http://dx.doi.org/10.1261/rna.061655.117