Cargando…

Antagonistic actions of two human Pan3 isoforms on global mRNA turnover

Deadenylation is a fundamental process that regulates eukaryotic gene expression. Mammalian deadenylation exhibits biphasic kinetics, with the Pan2–Pan3 and Ccr4–Caf1 deadenylase complexes mediating the first and second phase, respectively; however, the significance of the biphasic nature of deadeny...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Chyi-Ying A., Zhang, Yueqiang, Xiang, Yu, Han, Leng, Shyu, Ann-Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558910/
https://www.ncbi.nlm.nih.gov/pubmed/28559491
http://dx.doi.org/10.1261/rna.061556.117