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N(6)-methyladenosine is required for the hypoxic stabilization of specific mRNAs

Post-transcriptional regulation of mRNA during oxygen deprivation, or hypoxia, can affect the survivability of cells. Hypoxia has been shown to increase stability of a subset of ischemia-related mRNAs, including VEGF. RNA binding proteins and miRNAs have been identified as important for post-transcr...

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Detalles Bibliográficos
Autores principales: Fry, Nate J., Law, Brittany A., Ilkayeva, Olga R., Holley, Christopher L., Mansfield, Kyle D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558913/
https://www.ncbi.nlm.nih.gov/pubmed/28611253
http://dx.doi.org/10.1261/rna.061044.117