Cargando…

The hepatic circadian clock fine-tunes the lipogenic response to feeding through RORα/γ

Liver lipid metabolism is under intricate temporal control by both the circadian clock and feeding. The interplay between these two mechanisms is not clear. Here we show that liver-specific depletion of nuclear receptors RORα and RORγ, key components of the molecular circadian clock, up-regulate exp...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Yuxiang, Papazyan, Romeo, Damle, Manashree, Fang, Bin, Jager, Jennifer, Feng, Dan, Peed, Lindsey C., Guan, Dongyin, Sun, Zheng, Lazar, Mitchell A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558923/
https://www.ncbi.nlm.nih.gov/pubmed/28747429
http://dx.doi.org/10.1101/gad.302323.117