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Nuclear mTOR acts as a transcriptional integrator of the androgen signaling pathway in prostate cancer

Androgen receptor (AR) signaling reprograms cellular metabolism to support prostate cancer (PCa) growth and survival. Another key regulator of cellular metabolism is mTOR, a kinase found in diverse protein complexes and cellular localizations, including the nucleus. However, whether nuclear mTOR pla...

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Detalles Bibliográficos
Autores principales: Audet-Walsh, Étienne, Dufour, Catherine R., Yee, Tracey, Zouanat, Fatima Z., Yan, Ming, Kalloghlian, Georges, Vernier, Mathieu, Caron, Maxime, Bourque, Guillaume, Scarlata, Eleonora, Hamel, Lucie, Brimo, Fadi, Aprikian, Armen G., Lapointe, Jacques, Chevalier, Simone, Giguère, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558925/
https://www.ncbi.nlm.nih.gov/pubmed/28724614
http://dx.doi.org/10.1101/gad.299958.117