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Nuclear mTOR acts as a transcriptional integrator of the androgen signaling pathway in prostate cancer
Androgen receptor (AR) signaling reprograms cellular metabolism to support prostate cancer (PCa) growth and survival. Another key regulator of cellular metabolism is mTOR, a kinase found in diverse protein complexes and cellular localizations, including the nucleus. However, whether nuclear mTOR pla...
Autores principales: | Audet-Walsh, Étienne, Dufour, Catherine R., Yee, Tracey, Zouanat, Fatima Z., Yan, Ming, Kalloghlian, Georges, Vernier, Mathieu, Caron, Maxime, Bourque, Guillaume, Scarlata, Eleonora, Hamel, Lucie, Brimo, Fadi, Aprikian, Armen G., Lapointe, Jacques, Chevalier, Simone, Giguère, Vincent |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558925/ https://www.ncbi.nlm.nih.gov/pubmed/28724614 http://dx.doi.org/10.1101/gad.299958.117 |
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