Ferredoxin reductase is critical for p53-dependent tumor suppression via iron regulatory protein 2

Ferredoxin reductase (FDXR), a target of p53, modulates p53-dependent apoptosis and is necessary for steroidogenesis and biogenesis of iron–sulfur clusters. To determine the biological function of FDXR, we generated a Fdxr-deficient mouse model and found that loss of Fdxr led to embryonic lethality...

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Detalles Bibliográficos
Autores principales: Zhang, Yanhong, Qian, Yingjuan, Zhang, Jin, Yan, Wensheng, Jung, Yong-Sam, Chen, Mingyi, Huang, Eric, Lloyd, Kent, Duan, Yuyou, Wang, Jian, Liu, Gang, Chen, Xinbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558926/
https://www.ncbi.nlm.nih.gov/pubmed/28747430
http://dx.doi.org/10.1101/gad.299388.117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558926/
https://www.ncbi.nlm.nih.gov/pubmed/28747430
http://dx.doi.org/10.1101/gad.299388.117

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