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Ferredoxin reductase is critical for p53-dependent tumor suppression via iron regulatory protein 2

Ferredoxin reductase (FDXR), a target of p53, modulates p53-dependent apoptosis and is necessary for steroidogenesis and biogenesis of iron–sulfur clusters. To determine the biological function of FDXR, we generated a Fdxr-deficient mouse model and found that loss of Fdxr led to embryonic lethality...

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Detalles Bibliográficos
Autores principales:	Zhang, Yanhong, Qian, Yingjuan, Zhang, Jin, Yan, Wensheng, Jung, Yong-Sam, Chen, Mingyi, Huang, Eric, Lloyd, Kent, Duan, Yuyou, Wang, Jian, Liu, Gang, Chen, Xinbin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2017
Materias:	Research Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558926/ https://www.ncbi.nlm.nih.gov/pubmed/28747430 http://dx.doi.org/10.1101/gad.299388.117

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