Long-term persistent infection of HPV 16 E6 up-regulate SP1 and hTERT by inhibiting LKB1 in lung cancer cells

HPV 16 E6 upregulates hTERT expression in lung cancer cells. However, the underlying molecular mechanism is unclear. In this paper, E6, LKB1, SP1, and hTERT mRNA expression levels were detected in brushing cells of patients with lung cancer (n = 106) and with benign lung disease (n = 68) by qRT-PCR....

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Detalles Bibliográficos
Autores principales: Yang, Jing-Hua, Li, Xiao-Yan, Wang, Xin, Hou, Wei-Jian, Qiu, Xue-Shan, Wang, En-Hua, Wu, Guang-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558957/
https://www.ncbi.nlm.nih.gov/pubmed/28813465
http://dx.doi.org/10.1371/journal.pone.0182775

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558957/
https://www.ncbi.nlm.nih.gov/pubmed/28813465
http://dx.doi.org/10.1371/journal.pone.0182775

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