Comparison of homologous and heterologous prime-boost vaccine approaches using Modified Vaccinia Ankara and soluble protein to induce neutralizing antibodies by the human cytomegalovirus pentamer complex in mice

Since neutralizing antibodies (NAb) targeting the human cytomegalovirus (HCMV) pentamer complex (PC) potently block HCMV host cell entry, anti-PC NAb induction is thought to be important for a vaccine formulation to prevent HCMV infection. By developing a vaccine strategy based on soluble PC protein...

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Detalles Bibliográficos
Autores principales: Chiuppesi, Flavia, Wussow, Felix, Scharf, Louise, Contreras, Heidi, Gao, Han, Meng, Zhuo, Nguyen, Jenny, Barry, Peter A., Bjorkman, Pamela J., Diamond, Don J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558987/
https://www.ncbi.nlm.nih.gov/pubmed/28813507
http://dx.doi.org/10.1371/journal.pone.0183377

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558987/
https://www.ncbi.nlm.nih.gov/pubmed/28813507
http://dx.doi.org/10.1371/journal.pone.0183377

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