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Mycolactone cytotoxicity in Schwann cells could explain nerve damage in Buruli ulcer

Buruli ulcer is a chronic painless skin disease caused by Mycobacterium ulcerans. The local nerve damage induced by M. ulcerans invasion is similar to the nerve damage evoked by the injection of mycolactone in a Buruli ulcer mouse model. In order to elucidate the mechanism of this nerve damage, we t...

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Detalles Bibliográficos
Autores principales: En, Junichiro, Kitamoto, Sho, Kawashima, Akira, Yonezawa, Suguru, Kishi, Yoshito, Ishii, Norihisa, Goto, Masamichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559071/
https://www.ncbi.nlm.nih.gov/pubmed/28783752
http://dx.doi.org/10.1371/journal.pntd.0005834