D-cycloserine improves synaptic transmission in an animal mode of Rett syndrome

Rett syndrome (RTT), a leading cause of intellectual disability in girls, is predominantly caused by mutations in the X-linked gene MECP2. Disruption of Mecp2 in mice recapitulates major features of RTT, including neurobehavioral abnormalities, which can be reversed by re-expression of normal Mecp2....

Descripción completa

Detalles Bibliográficos
Autores principales: Na, Elisa S., De Jesús-Cortés, Héctor, Martinez-Rivera, Arlene, Kabir, Zeeba D., Wang, Jieqi, Ramesh, Vijayashree, Onder, Yasemin, Rajadhyaksha, Anjali M., Monteggia, Lisa M., Pieper, Andrew A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559075/
https://www.ncbi.nlm.nih.gov/pubmed/28813484
http://dx.doi.org/10.1371/journal.pone.0183026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559075/
https://www.ncbi.nlm.nih.gov/pubmed/28813484
http://dx.doi.org/10.1371/journal.pone.0183026

Ejemplares similares