Joint Analysis of Nuclear and Mitochondrial Variants in Age-Related Macular Degeneration Identifies Novel Loci TRPM1 and ABHD2/RLBP1

PURPOSE: Presently, 52 independent nuclear single nucleotide polymorphisms (nSNPs) have been associated with age-related macular degeneration (AMD) but their effects do not explain all its variance. Genetic interactions between the nuclear and mitochondrial (mt) genome may unearth additional genetic...

Descripción completa

Detalles Bibliográficos
Autores principales: Persad, Patrice J., Heid, Iris M., Weeks, Daniel E., Baird, Paul N., de Jong, Eiko K., Haines, Jonathan L., Pericak-Vance, Margaret A., Scott, William K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2017
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559178/
https://www.ncbi.nlm.nih.gov/pubmed/28813576
http://dx.doi.org/10.1167/iovs.17-21734

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559178/
https://www.ncbi.nlm.nih.gov/pubmed/28813576
http://dx.doi.org/10.1167/iovs.17-21734

Ejemplares similares