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A human PET study of [(11)C]HMS011, a potential radioligand for AMPA receptors

BACKGROUND: α-Amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptor is a primary mediator of fast glutamatergic excitatory signaling in the brain and has been implicated in diverse neuropsychiatric diseases. We recently developed a novel positron emission tomography (PET) ligand, 2-(1-(3-(...

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Detalles Bibliográficos
Autores principales: Takahata, Keisuke, Kimura, Yasuyuki, Seki, Chie, Tokunaga, Masaki, Ichise, Masanori, Kawamura, Kazunori, Ono, Maiko, Kitamura, Soichiro, Kubota, Manabu, Moriguchi, Sho, Ishii, Tatsuya, Takado, Yuhei, Niwa, Fumitoshi, Endo, Hironobu, Nagashima, Tomohisa, Ikoma, Yoko, Zhang, Ming-Rong, Suhara, Tetsuya, Higuchi, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559406/
https://www.ncbi.nlm.nih.gov/pubmed/28815446
http://dx.doi.org/10.1186/s13550-017-0313-0