Cargando…

A comparative sequence analysis reveals a common GBD/FH3-FH1-FH2-DAD architecture in formins from Dictyostelium, fungi and metazoa

BACKGROUND: Formins are multidomain proteins defined by a conserved FH2 (formin homology 2) domain with actin nucleation activity preceded by a proline-rich FH1 (formin homology 1) domain. Formins act as profilin-modulated processive actin nucleators conserved throughout a wide range of eukaryotes....

Descripción completa

Detalles Bibliográficos
Autores principales: Rivero, Francisco, Muramoto, Tetsuya, Meyer, Ann-Kathrin, Urushihara, Hideko, Uyeda, Taro QP, Kitayama, Chikako
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC555941/
https://www.ncbi.nlm.nih.gov/pubmed/15740615
http://dx.doi.org/10.1186/1471-2164-6-28