Increased Body Exposure to New Anti-Trypanosomal Through Nanoencapsulation

Lychnopholide, a lipophilic sesquiterpene lactone, is efficacious in mice at the acute and chronic phases of Chagas disease. Conventional poly-ε-caprolactone (PCL) and long-circulating poly(D,L-lactide)-block-polyethylene glycol (PLA-PEG) nanocapsules containing lychnopholide were developed and char...

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Detalles Bibliográficos
Autores principales: Tupinambá Branquinho, Renata, Pound-Lana, Gwenaelle, Marques Milagre, Matheus, Saúde-Guimarães, Dênia Antunes, Vilela, José Mário Carneiro, Spangler Andrade, Margareth, de Lana, Marta, Mosqueira, Vanessa Carla Furtado
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559493/
https://www.ncbi.nlm.nih.gov/pubmed/28814794
http://dx.doi.org/10.1038/s41598-017-08469-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559493/
https://www.ncbi.nlm.nih.gov/pubmed/28814794
http://dx.doi.org/10.1038/s41598-017-08469-x

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