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CRISPR-Cas9 Mediated Labelling Allows for Single Molecule Imaging and Resolution
Single molecule imaging approaches like dSTORM and PALM resolve structures at 10–20 nm, and allow for unique insights into protein stoichiometry and spatial relationships. However, key obstacles remain in developing highly accurate quantitative single molecule approaches. The genomic tagging of PALM...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559501/ https://www.ncbi.nlm.nih.gov/pubmed/28814796 http://dx.doi.org/10.1038/s41598-017-08493-x |