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CRISPR-Cas9 Mediated Labelling Allows for Single Molecule Imaging and Resolution

Single molecule imaging approaches like dSTORM and PALM resolve structures at 10–20 nm, and allow for unique insights into protein stoichiometry and spatial relationships. However, key obstacles remain in developing highly accurate quantitative single molecule approaches. The genomic tagging of PALM...

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Detalles Bibliográficos
Autores principales: Khan, Abdullah O., Simms, Victoria A., Pike, Jeremy A., Thomas, Steven G., Morgan, Neil V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559501/
https://www.ncbi.nlm.nih.gov/pubmed/28814796
http://dx.doi.org/10.1038/s41598-017-08493-x