Strain-dependence of the Angelman Syndrome phenotypes in Ube3a maternal deficiency mice

Angelman syndrome (AS) is a genetic neurodevelopmental disorder, most commonly caused by deletion or mutation of the maternal allele of the UBE3A gene, with behavioral phenotypes and seizures as key features. Currently no treatment is available, and therapeutics are often ineffective in controlling...

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Detalles Bibliográficos
Autores principales: Born, Heather A., Dao, An T., Levine, Amber T., Lee, Wai Ling, Mehta, Natasha M., Mehra, Shubhangi, Weeber, Edwin J., Anderson, Anne E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559514/
https://www.ncbi.nlm.nih.gov/pubmed/28814801
http://dx.doi.org/10.1038/s41598-017-08825-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559514/
https://www.ncbi.nlm.nih.gov/pubmed/28814801
http://dx.doi.org/10.1038/s41598-017-08825-x

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