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The BEACH Protein LRBA Promotes the Localization of the Heterotrimeric G-protein G(olf) to Olfactory Cilia

BEACH domain proteins are involved in membrane protein traffic and human diseases, but their molecular mechanisms are not understood. The BEACH protein LRBA has been implicated in immune response and cell proliferation, and human LRBA mutations cause severe immune deficiency. Here, we report a first...

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Detalles Bibliográficos
Autores principales: Kurtenbach, Stefan, Gießl, Andreas, Strömberg, Siv, Kremers, Jan, Atorf, Jenny, Rasche, Sebastian, Neuhaus, Eva M., Hervé, Denis, Brandstätter, Johann Helmut, Asan, Esther, Hatt, Hanns, Kilimann, Manfred W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559528/
https://www.ncbi.nlm.nih.gov/pubmed/28814779
http://dx.doi.org/10.1038/s41598-017-08543-4