Social isolation suppresses actin dynamics and synaptic plasticity through ADF/cofilin inactivation in the developing rat barrel cortex

Exposure to a stressful environment early in life can cause psychiatric disorders by disrupting circuit formation. Actin plays central roles in regulating neuronal structure and protein trafficking. We have recently reported that neonatal isolation inactivated ADF/cofilin, the actin depolymerizing f...

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Detalles Bibliográficos
Autores principales: Tada, Hirobumi, Miyazaki, Tomoyuki, Takemoto, Kiwamu, Jitsuki, Susumu, Nakajima, Waki, Koide, Mayu, Yamamoto, Naoko, Taguchi, Akiko, Kawai, Honami, Komiya, Kasane, Suyama, Kumiko, Abe, Hiroki, Sano, Akane, Takahashi, Takuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559554/
https://www.ncbi.nlm.nih.gov/pubmed/28814784
http://dx.doi.org/10.1038/s41598-017-08849-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559554/
https://www.ncbi.nlm.nih.gov/pubmed/28814784
http://dx.doi.org/10.1038/s41598-017-08849-3

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