RNA sequencing of db/db mice liver identifies lncRNA H19 as a key regulator of gluconeogenesis and hepatic glucose output

Liver plays a key role in maintaining glucose homeostasis and impaired hepatic glucose metabolism is associated with type 2 diabetes. In the present study, we used RNA sequencing to profile the transcriptome of the livers of diabetic db/db mice as compared to the normal db/+ mice and identified 218...

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Detalles Bibliográficos
Autores principales: Goyal, Neha, Sivadas, Ambily, Shamsudheen, K. V., Jayarajan, Rijith, Verma, Ankit, Sivasubbu, Sridhar, Scaria, Vinod, Datta, Malabika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559625/
https://www.ncbi.nlm.nih.gov/pubmed/28814771
http://dx.doi.org/10.1038/s41598-017-08281-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559625/
https://www.ncbi.nlm.nih.gov/pubmed/28814771
http://dx.doi.org/10.1038/s41598-017-08281-7

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