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RNA sequencing of db/db mice liver identifies lncRNA H19 as a key regulator of gluconeogenesis and hepatic glucose output
Liver plays a key role in maintaining glucose homeostasis and impaired hepatic glucose metabolism is associated with type 2 diabetes. In the present study, we used RNA sequencing to profile the transcriptome of the livers of diabetic db/db mice as compared to the normal db/+ mice and identified 218...
Autores principales: | Goyal, Neha, Sivadas, Ambily, Shamsudheen, K. V., Jayarajan, Rijith, Verma, Ankit, Sivasubbu, Sridhar, Scaria, Vinod, Datta, Malabika |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559625/ https://www.ncbi.nlm.nih.gov/pubmed/28814771 http://dx.doi.org/10.1038/s41598-017-08281-7 |
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