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Quantification of lactate from various metabolic pathways and quantification issues of lactate isotopologues and isotopmers
(13)C-labeled glucose combined with chromatography and mass spectrometry enables us to decipher the percentage of lactate generated from various metabolic pathways. We showed that lactate derived from glycolysis, pentose phosphate pathway, Krebs cycle, and other sources accounted for 82–90%, 6.0–11%...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559627/ https://www.ncbi.nlm.nih.gov/pubmed/28814730 http://dx.doi.org/10.1038/s41598-017-08277-3 |