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The Capacity of Mycobacterium tuberculosis To Survive Iron Starvation Might Enable It To Persist in Iron-Deprived Microenvironments of Human Granulomas

This study was conducted to investigate the role of iron deprivation in the persistence of Mycobacterium tuberculosis. We present evidence of iron restriction in human necrotic granulomas and demonstrate that under iron starvation M. tuberculosis persists, refractive to antibiotics and capable of re...

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Detalles Bibliográficos
Autores principales: Kurthkoti, Krishna, Amin, Hamel, Marakalala, Mohlopheni J., Ghanny, Saleena, Subbian, Selvakumar, Sakatos, Alexandra, Livny, Jonathan, Fortune, Sarah M., Berney, Michael, Rodriguez, G. Marcela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559634/
https://www.ncbi.nlm.nih.gov/pubmed/28811344
http://dx.doi.org/10.1128/mBio.01092-17