Inhibitors of the Histone Methyltransferases EZH2/1 Induce a Potent Antiviral State and Suppress Infection by Diverse Viral Pathogens

Epigenetic regulation is based on a network of complexes that modulate the chromatin character and structure of the genome to impact gene expression, cell fate, and development. Thus, epigenetic modulators represent novel therapeutic targets used to treat a range of diseases, including malignancies....

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Detalles Bibliográficos
Autores principales: Arbuckle, Jesse H., Gardina, Paul J., Gordon, David N., Hickman, Heather D., Yewdell, Jonathan W., Pierson, Theodore C., Myers, Timothy G., Kristie, Thomas M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559635/
https://www.ncbi.nlm.nih.gov/pubmed/28811345
http://dx.doi.org/10.1128/mBio.01141-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559635/
https://www.ncbi.nlm.nih.gov/pubmed/28811345
http://dx.doi.org/10.1128/mBio.01141-17

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