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A Critical Role of Glutamine and Asparagine γ-Nitrogen in Nucleotide Biosynthesis in Cancer Cells Hijacked by an Oncogenic Virus

While glutamine is a nonessential amino acid that can be synthesized from glucose, some cancer cells primarily depend on glutamine for their growth, proliferation, and survival. Numerous types of cancer also depend on asparagine for cell proliferation. The underlying mechanisms of the glutamine and...

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Detalles Bibliográficos
Autores principales: Zhu, Ying, Li, Tingting, Ramos da Silva, Suzane, Lee, Jae-Jin, Lu, Chun, Eoh, Hyungjin, Jung, Jae U., Gao, Shou-Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559638/
https://www.ncbi.nlm.nih.gov/pubmed/28811348
http://dx.doi.org/10.1128/mBio.01179-17