Critical appraisal of arguments for the delayed-start design proposed as alternative to the parallel-group randomized clinical trial design in the field of rare disease

BACKGROUND: A number of papers have proposed or evaluated the delayed-start design as an alternative to the standard two-arm parallel group randomized clinical trial (RCT) design in the field of rare disease. However the discussion is felt to lack a sufficient degree of consideration devoted to the...

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Detalles Bibliográficos
Autores principales: Spineli, Loukia M., Jenz, Eva, Großhennig, Anika, Koch, Armin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Position Statement
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559817/
https://www.ncbi.nlm.nih.gov/pubmed/28814322
http://dx.doi.org/10.1186/s13023-017-0692-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559817/
https://www.ncbi.nlm.nih.gov/pubmed/28814322
http://dx.doi.org/10.1186/s13023-017-0692-3

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