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Cancerouspdomains: comprehensive analysis of cancer type-specific recurrent somatic mutations in proteins and domains
BACKGROUND: Discriminating driver mutations from the ones that play no role in cancer is a severe bottleneck in elucidating molecular mechanisms underlying cancer development. Since protein domains are representatives of functional regions within proteins, mutations on them may disturb the protein f...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559820/ https://www.ncbi.nlm.nih.gov/pubmed/28814324 http://dx.doi.org/10.1186/s12859-017-1779-5 |