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The role of amyloid beta clearance in cerebral amyloid angiopathy: more potential therapeutic targets

Cerebral amyloid angiopathy (CAA) is characterized by the deposition of amyloid β-protein (Aβ) in the leptomeningeal and cortical blood vessels, which is an age-dependent risk factor for intracerebral hemorrhage (ICH), ischemic stroke and contributes to cerebrovascular dysfunction leading to cogniti...

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Detalles Bibliográficos
Autores principales: Qi, Xue-mei, Ma, Jian-fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559841/
https://www.ncbi.nlm.nih.gov/pubmed/28824801
http://dx.doi.org/10.1186/s40035-017-0091-7