Antioxidant Treatment in Male Mice Prevents Mitochondrial and Synaptic Changes in an NMDA Receptor Dysfunction Model of Schizophrenia

Glutamate theories of schizophrenia suggest that the disease is associated with a loss of NMDA receptors, specifically on GABAergic parvalbumin-expressing interneurons (PVIs), leading to changes in the excitation–inhibition balance in the prefrontal cortex (PFC). Oxidative stress contributes to the...

Descripción completa

Detalles Bibliográficos
Autores principales: Phensy, Aarron, Driskill, Christopher, Lindquist, Karen, Guo, Lan, Jeevakumar, Vivek, Fowler, Bryan, Du, Heng, Kroener, Sven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2017
Materias:
New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559903/
https://www.ncbi.nlm.nih.gov/pubmed/28819639
http://dx.doi.org/10.1523/ENEURO.0081-17.2017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559903/
https://www.ncbi.nlm.nih.gov/pubmed/28819639
http://dx.doi.org/10.1523/ENEURO.0081-17.2017

Ejemplares similares