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Antioxidant Treatment in Male Mice Prevents Mitochondrial and Synaptic Changes in an NMDA Receptor Dysfunction Model of Schizophrenia
Glutamate theories of schizophrenia suggest that the disease is associated with a loss of NMDA receptors, specifically on GABAergic parvalbumin-expressing interneurons (PVIs), leading to changes in the excitation–inhibition balance in the prefrontal cortex (PFC). Oxidative stress contributes to the...
Autores principales: | Phensy, Aarron, Driskill, Christopher, Lindquist, Karen, Guo, Lan, Jeevakumar, Vivek, Fowler, Bryan, Du, Heng, Kroener, Sven |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559903/ https://www.ncbi.nlm.nih.gov/pubmed/28819639 http://dx.doi.org/10.1523/ENEURO.0081-17.2017 |
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