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A Pilot Genome-Wide Association Study in Postmenopausal Mexican-Mestizo Women Implicates the RMND1/CCDC170 Locus Is Associated with Bone Mineral Density

To identify genetic variants influencing bone mineral density (BMD) in the Mexican-Mestizo population, we performed a GWAS for femoral neck (FN) and lumbar spine (LS) in Mexican-Mestizo postmenopausal women. In the discovery sample, 300,000 SNPs were genotyped in a cohort of 411 postmenopausal women...

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Detalles Bibliográficos
Autores principales: Villalobos-Comparán, Marisela, Jiménez-Ortega, Rogelio F., Estrada, Karol, Parra-Torres, Alma Y., González-Mercado, Anahí, Patiño, Nelly, Castillejos-López, Manuel, Quiterio, Manuel, Fernandez-López, Juan Carlos, Ibarra, Bertha, Romero-Hidalgo, Sandra, Salmerón, Jorge, Velázquez-Cruz, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559934/
https://www.ncbi.nlm.nih.gov/pubmed/28840121
http://dx.doi.org/10.1155/2017/5831020