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A Role for The ATP7A Copper Transporter in Tumorigenesis and Cisplatin Resistance

The ATP7A protein is a ubiquitously expressed copper-translocating P-type ATPase that controls cytoplasmic copper concentrations by mediating cellular copper egress. In vitro studies have previously demonstrated that ATP7A abundance in various tumor cell lines is correlated with increased resistance...

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Detalles Bibliográficos
Autores principales: Zhu, Sha, Shanbhag, Vinit, Wang, Yanfang, Lee, Jaekwon, Petris, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559955/
https://www.ncbi.nlm.nih.gov/pubmed/28819394
http://dx.doi.org/10.7150/jca.19029