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Downregulation of ABC Transporters in Non-neoplastic Tissues Confers Better Prognosis for Pancreatic and Colorectal Cancer Patients

Transport of a wide variety of substrates, including xenobiotics, is one of the main functions attributed to human ATP-binding cassette (ABC) proteins. Overexpression of ABC genes is considered to be an important mechanism facilitating the development of chemoresistance. Relationships between the ex...

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Detalles Bibliográficos
Autores principales: Dvorak, Pavel, Hlavac, Viktor, Mohelnikova-Duchonova, Beatrice, Liska, Vaclav, Pesta, Martin, Soucek, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559956/
https://www.ncbi.nlm.nih.gov/pubmed/28819395
http://dx.doi.org/10.7150/jca.19364