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PD-L1 Expression Is Associated with FOXP3+ Regulatory T-Cell Infiltration of Soft Tissue Sarcoma and Poor Patient Prognosis

Background: Programmed death ligand-1(PD-L1) functions as a negative mediator of immune response through different pathways in anti-tumor immunity. Recent studies have reported that PD-L1 plays a pivotal role in the function of regulatory T-cells (Tregs). Although increases in FOXP3+ Tregs infiltrat...

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Detalles Bibliográficos
Autores principales: Que, Yi, Xiao, Wei, Guan, Yuan-xiang, Liang, Yao, Yan, Shu-mei, Chen, Huo-ying, Li, Qiao-qiao, Xu, Bu-shu, Zhou, Zhi-wei, Zhang, Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559963/
https://www.ncbi.nlm.nih.gov/pubmed/28819402
http://dx.doi.org/10.7150/jca.18683