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CENPH Inhibits Rapamycin Sensitivity by Regulating GOLPH3-dependent mTOR Signaling Pathway in Colorectal Cancer

Background: Centromere protein H (CENPH) is known as a fundamental component of the active centromere complex, and its overexpression is correlated with poor prognosis in various solid tumors. mTOR inhibitor rapamycin has been shown to possess antitumor activity, as well as prevent intestinal tumori...

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Detalles Bibliográficos
Autores principales: Wu, Wei, Wu, Fan, Wang, Zaozao, Di, Jiabo, Yang, Jie, Gao, Pin, Jiang, Beihai, Su, Xiangqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560133/
https://www.ncbi.nlm.nih.gov/pubmed/28819418
http://dx.doi.org/10.7150/jca.19940