Interactions between Quinolones and Bacillus anthracis Gyrase and the Basis of Drug Resistance

[Image: see text] Gyrase appears to be the primary cellular target for quinolone antibacterials in multiple pathogenic bacteria, including Bacillus anthracis, the causative agent of anthrax. Given the significance of this type II topoisomerase as a drug target, it is critical to understand how quino...

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Detalles Bibliográficos
Autores principales: Ashley, Rachel E., Lindsey, R. Hunter, McPherson, Sylvia A., Turnbough, Charles L., Kerns, Robert J., Osheroff, Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560241/
https://www.ncbi.nlm.nih.gov/pubmed/28708938
http://dx.doi.org/10.1021/acs.biochem.7b00203

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560241/
https://www.ncbi.nlm.nih.gov/pubmed/28708938
http://dx.doi.org/10.1021/acs.biochem.7b00203

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