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Interactions between Quinolones and Bacillus anthracis Gyrase and the Basis of Drug Resistance
[Image: see text] Gyrase appears to be the primary cellular target for quinolone antibacterials in multiple pathogenic bacteria, including Bacillus anthracis, the causative agent of anthrax. Given the significance of this type II topoisomerase as a drug target, it is critical to understand how quino...
Autores principales: | Ashley, Rachel E., Lindsey, R. Hunter, McPherson, Sylvia A., Turnbough, Charles L., Kerns, Robert J., Osheroff, Neil |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560241/ https://www.ncbi.nlm.nih.gov/pubmed/28708938 http://dx.doi.org/10.1021/acs.biochem.7b00203 |
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