Comparing efficacies of moxifloxacin, levofloxacin and gatifloxacin in tuberculosis granulomas using a multi-scale systems pharmacology approach

Granulomas are complex lung lesions that are the hallmark of tuberculosis (TB). Understanding antibiotic dynamics within lung granulomas will be vital to improving and shortening the long course of TB treatment. Three fluoroquinolones (FQs) are commonly prescribed as part of multi-drug resistant TB...

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Detalles Bibliográficos
Autores principales: Pienaar, Elsje, Sarathy, Jansy, Prideaux, Brendan, Dietzold, Jillian, Dartois, Véronique, Kirschner, Denise E., Linderman, Jennifer J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560534/
https://www.ncbi.nlm.nih.gov/pubmed/28817561
http://dx.doi.org/10.1371/journal.pcbi.1005650

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560534/
https://www.ncbi.nlm.nih.gov/pubmed/28817561
http://dx.doi.org/10.1371/journal.pcbi.1005650

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