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Rac2 is required for alternative macrophage activation and bleomycin induced pulmonary fibrosis; a macrophage autonomous phenotype

Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease characterized by cellular phenotype alterations and deposition of extracellular matrix proteins. The alternative activation of macrophages in the lungs has been associated as a major factor promoting pulmonary fibrosis, however the mechan...

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Detalles Bibliográficos
Autores principales: Joshi, Shweta, Singh, Alok R., Wong, Simon S., Zulcic, Muamera, Jiang, Min, Pardo, Annie, Selman, Moises, Hagood, James S., Durden, Donald L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560537/
https://www.ncbi.nlm.nih.gov/pubmed/28817691
http://dx.doi.org/10.1371/journal.pone.0182851