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Rac2 is required for alternative macrophage activation and bleomycin induced pulmonary fibrosis; a macrophage autonomous phenotype
Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease characterized by cellular phenotype alterations and deposition of extracellular matrix proteins. The alternative activation of macrophages in the lungs has been associated as a major factor promoting pulmonary fibrosis, however the mechan...
Autores principales: | Joshi, Shweta, Singh, Alok R., Wong, Simon S., Zulcic, Muamera, Jiang, Min, Pardo, Annie, Selman, Moises, Hagood, James S., Durden, Donald L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560537/ https://www.ncbi.nlm.nih.gov/pubmed/28817691 http://dx.doi.org/10.1371/journal.pone.0182851 |
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