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All-trans retinoic acid suppresses malignant characteristics of CD133-positive thyroid cancer stem cells and induces apoptosis

Recently, diagnoses of radioiodine-refractory differentiated thyroid cancer (RAI-R DTC) have become more common; prognosis is poor. It has been suggested that cancer stem cells account for radiotherapy resistance. By flow cytometry, different expression percents of CD133 and OCT4 in thyroid cancer c...

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Detalles Bibliográficos
Autores principales: Mei, Dan, Lv, Bin, Chen, Bo, Xiao, Shan, Jiang, Jie, Xie, Yan, Jiang, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560547/
https://www.ncbi.nlm.nih.gov/pubmed/28817605
http://dx.doi.org/10.1371/journal.pone.0182835